Bill Gates pledges $12 million for universal flu vaccine research — but will it be enough?
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Bill Gates has pledged $12 million in funding to fuel advances toward a universal flu vaccine, STAT News reports. After this year’s devastating flu season,
the race for a shot that could protect against a broad range of flu
viruses for years on end feels even more urgent — but is $12 million
really enough to help?
Gates announced the funding today at a conference. Half
would come from the Bill & Melinda Gates Foundation, and the other
half would be from the family of Google co-founder Larry Page. The money
would be doled out in grants of up to $2 million for individual
projects “that are bold and innovative,” the funding website says.
The idea is that the $2 million, paid over two years,
would be enough money for researchers to collect preliminary data in
animal models. And then the most promising strategies could be eligible
to apply for up to another $10 million to take the vaccine candidates to
human trials. The foundation is looking for proposals that could be
ready to start clinical trials by 2021.
Still, the $12 million in seed money seems like a small drop in the flood of funding needed for vaccine development, STAT points out.
The National Institutes of Allergy and Infectious Disease spent $64
million on universal flu vaccine research in the 2017 fiscal year alone,
according to Bloomberg. And a year without a flu season could still be at least a decade away.
The funding proposal also takes aim at the wrong part of the race, according to NPR:
there are plenty of promising candidates at the starting line, but
fewer have enough funding to actually make it into clinical trials — a
key hurdle en route to the finish. ‘’The real bottleneck is getting
these experimental vaccines into testing in humans, and that is a very
expensive undertaking,” vaccine researcher Sarah Gilbert told NPR.
Still, the Bill & Melinda Gates Foundation is funding those efforts from other pots of money. The charity has given more than $9.5 million
to support the Icahn School of Medicine at Mount Sinai’s efforts to
take a universal flu vaccine into human trials, for example. Florian Krammer,
a microbiology professor at Mount Sinai who’s working on this project,
joked that the team would still be vaccinating mice without the
foundation’s support. “They enabled us to start testing our vaccine in
humans,” he said in an email to The Verge. He called today’s announcement “a very good step in the right direction.”
Paul Radspinner, president and CEO of FluGen,
a company that’s working on a candidate universal flu vaccine that uses
a genetically modified flu virus, said that today’s announcement was a
win for the field. “Having the Gates Foundation throw its weight behind
the search for a universal flu vaccine is fantastic news,” he said in an
email to The Verge. “We’re not concerned about the size of the
investment as I’m sure this is just the first of many announcements by
the Foundation about how they will play a significant role in this
area.”
Gates himself echoed that sentiment, in an interview with STAT. “This is the early-stage money,” he said. “This $12 million isn’t the end of the game
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